Minoxidil may suppress androgen receptor-related functions

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Minoxidil may suppress androgen receptor-related functions

Although minoxidil has been used for more than two decades to treat androgenetic alopecia (AGA), an androgen-androgen receptor (AR) pathway-dominant disease, its precise mechanism of action remains elusive. We hypothesized that minoxidil may influence the AR or its downstream signaling. These tests revealed that minoxidil suppressed AR-related functions, decreasing AR transcriptional activity i...

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2014

ISSN: 1949-2553

DOI: 10.18632/oncotarget.1886